產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-Cdx1 antibody (1-100) [S2MR] (STJ11103662)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-Cdx1 (1-100) is suitable for use in Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | S2MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CDX1 |
Gene ID: | 1044 |
Uniprot ID: | CDX1_HUMAN |
Immunogen Region: | 1-100 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cdx1 (P47902). |
Immunogen Sequence: | MYVGYVLDKDSPVYPGPARP ASLGLGPQAYGPPAPPPAPP QYPDFSSYSHVEPAPAPPTA WGAPFPAPKDDWAAAYGPGP AAPAASPASLAFGPPPDFSP |
Tissue Specificity | Intestinal epithelium. |
Function | Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA. |
Protein Name | Homeobox Protein Cdx-1 Caudal-Type Homeobox Protein 1 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Homeobox Protein Cdx-1 antibody Anti-Caudal-Type Homeobox Protein 1 antibody Anti-CDX1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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