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產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Anti-EDN1 antibody (131-180 aa) (STJ96512)

  • 產(chǎn)品型號(hào)：STJ96512
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-EDN1 antibody (131-180 aa) (STJ96512)
詳情介紹：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Endothelin-1 (131-180 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 100-300
WB 1:500-1:2000
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EDN1
Gene ID: 1906
Uniprot ID: EDN1_HUMAN
Immunogen Region: 131-180 aa
Specificity: ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1 at the amino acid range 131-180
Function Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Also binds the DEAR/FBXW7-AS1 receptor.
Protein Name Endothelin-1
Preproendothelin-1
Ppet1 Cleaved Into - Endothelin-1
Et-1 - Big Endothelin-1
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Cellular Localisation Secreted
Alternative Antibody Names Anti-Endothelin-1 antibody
Anti-Preproendothelin-1 antibody
Anti-Ppet1 Cleaved Into - Endothelin-1 antibody
Anti-Et-1 - Big Endothelin-1 antibody
Anti-EDN1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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