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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-CD3E+CD3G antibody (1-207) [S3942RM] (STJ11103942)

  • 產(chǎn)品型號(hào)：STJ11103942
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Anti-CD3E+CD3G antibody (1-207) [S3942RM] (STJ11103942)
詳情介紹：
Host: Rabbit
Applications: WB/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-CD3E+CD3G (1-207) is suitable for use in Western Blot and Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: S3942RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
FC 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunogen Region: 1-207
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 (CD3E) & 1-182 (CD3G) of human CD3 epsilon&CD3 gamma Heterodimer.
Immunogen Sequence: MQSGTHWRVLGLCLLSVGVW GQDGNEEMGGITQTPYKVSI SGTTVILTCPQYPGSEILWQ HNDKNIGGDEDDKNIGSDED HLSLKEFSELEQSGYYVCYP RGSKPEDANFYLYLRARVCE NCMEMDVMSVATIVIVDICI TGGLLLLVYYWSKNRKAKAK PVTRGAGAGGRQRGQNKERP PPVPNPDYEPIRKGQRDLYS GLNQRRI (CD3E) &MEQGKG LAVLILAIILLQGTLAQ
Background The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma,-delta and-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon,-delta and-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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