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產(chǎn)品詳情

  • 產(chǎn)品名稱：Mouse Viperin (Viperin) Sandwich ELISA Kit (STJE0013047)

  • 產(chǎn)品型號：STJE0013047
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡單介紹：
Mouse Viperin (Viperin) Sandwich ELISA Kit (STJE0013047)
詳情介紹：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.072ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This Viperin Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Rsad2
Gene ID: 58185
Uniprot ID: RSAD2_MOUSE
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed at higher levels in atherosclerotic arteries than in normal arteries.
Post Translational Modifications Acetylated by HAT1. HAT1-mediated acetylation of Lys-198 in turn recruits UBE4A that stimulates RSAD2 polyubiquitination leading to proteasomal degradation. 'Lys-6'-linked polyubiquitination at Lys-207 leads to RSAD2 protein degradation.
Function Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Catalyzes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP) via a SAM-dependent radical mechanism. In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication. Therefore, inhibits a wide range of DNA and RNA viruses. Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.
Protein Name S-Adenosylmethionine-Dependent Nucleotide Dehydratase Rsad2
Sand
Radical S-Adenosyl Methionine Domain-Containing Protein 2
Virus Inhibitory Protein - Endoplasmic Reticulum-Associated - Interferon-Inducible
Viperin
Database Links
Cellular Localisation Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Golgi Apparatus
Endoplasmic Reticulum
Lipid Droplet
Mitochondrion
Mitochondrion Inner Membrane
Mitochondrion Outer Membrane
Alternative ELISA Names S-Adenosylmethionine-Dependent Nucleotide Dehydratase Rsad2 ELISA kit
Sand ELISA kit
Radical S-Adenosyl Methionine Domain-Containing Protein 2 ELISA kit
Virus Inhibitory Protein - Endoplasmic Reticulum-Associated - Interferon-Inducible ELISA kit
Viperin ELISA kit
Rsad2 ELISA kit
Vig1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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