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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-FASN antibody [2F9-B2-B6] (STJ99046)

  • 產(chǎn)品型號(hào)：STJ99046
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-FASN antibody [2F9-B2-B6] (STJ99046)
詳情介紹：
Host: Mouse
Applications: WB/IP/IF
Reactivity: Human/Mouse/Rat/Monkey/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Fatty acid synthase S-acetyltransferase; S-malonyltransferase; 3-oxoacyl-acyl-carrier-protein synthase; 3-oxoacyl-acyl-carrier-protein reductase; 3-hydroxyacyl-acyl-carrier-protein dehydratase; Enoyl-acyl-carrier-protei
Clonality: Monoclonal
Clone ID: 2F9-B2-B6
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000
ICC 1:400
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FASN
Gene ID: 2194
Uniprot ID: FAS_HUMAN
Specificity: This antibody detects endogenous levels of Fatty Acid Synthase and does not cross-react with related proteins.
Immunogen: Purified recombinant human Fatty Acid Synthase protein fragments expressed in E.coli.
Post Translational Modifications S-nitrosylation of Fatty acid synthase at cysteine residues Cys-1471 or Cys-2091 is important for the enzyme dimerization. In adipocytes, S-nitrosylation of Fatty acid synthase occurs under physiological conditions and gradually increases during adipogenesis.
Function Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein (ACP) domain. (Microbial infection) Fatty acid synthetase activity is required for SARS coronavirus-2/SARS-CoV-2 replication.
Protein Name Fatty Acid Synthase
Type I Fatty Acid Synthase Includes - Acyl-Carrier-Protein S-Acetyltransferase - Acyl-Carrier-Protein S-Malonyltransferase - 3-Oxoacyl-Acyl-Carrier-Protein Synthase - 3-Oxoacyl-Acyl-Carrier-Protein Reductase - 3-Hydroxyacyl-Acyl-Carrier-Protein Dehydratase - Enoyl-Acyl-Carrier-Protein Reductase - Acyl-Acyl-Carrier-Protein Hydrolase
Database Links Reactome: R-HSA-163765
Reactome: R-HSA-199220
Reactome: R-HSA-2426168
Reactome: R-HSA-75105
Reactome: R-HSA-9029558
Cellular Localisation Cytoplasm
Melanosome
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names Anti-Fatty Acid Synthase antibody
Anti-Type I Fatty Acid Synthase Includes - Acyl-Carrier-Protein S-Acetyltransferase - Acyl-Carrier-Protein S-Malonyltransferase - 3-Oxoacyl-Acyl-Carrier-Protein Synthase - 3-Oxoacyl-Acyl-Carrier-Protein Reductase - 3-Hydroxyacyl-Acyl-Carrier-Protein Dehydratase - Enoyl-Acyl-Carrier-Protein Reductase - Acyl-Acyl-Carrier-Protein Hydrolase antibody
Anti-FASN antibody
Anti-FAS antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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