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產(chǎn)品詳情

  • 產(chǎn)品名稱：Mouse VCAM1 (Vascular Cell Adhesion Molecule 1) Sandwich ELISA Kit Ready-To-Use (STJE0006941)

  • 產(chǎn)品型號(hào)：STJE0006941
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Mouse VCAM1 (Vascular Cell Adhesion Molecule 1) Sandwich ELISA Kit Ready-To-Use (STJE0006941)
詳情介紹：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.23ng/mL
Detection Limit: 0.39-25ng/mL
Short Description: This VCAM1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Vcam1Uniprot ID=VCAM1_MOUSE"
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Expressed in the bone marrow.
Post Translational Modifications Cleaved by the metalloproteinase ADAM17 to generate the soluble form. Sialoglycoprotein. Ubiquitinated by TRIM65 via 'Lys-48'-linked ubiquitination.leading to proteasomal degradation.
Function Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation.
Protein Name Vascular Cell Adhesion Protein 1
V-Cam 1
Vcam-1
Cd Antigen Cd106 Cleaved Into - Soluble Vascular Cell Adhesion Molecule-1
Database Links
Cellular Localisation Vascular Cell Adhesion Protein 1: Cell Membrane
Single-Pass Type I Membrane Protein
Soluble Vascular Cell Adhesion Molecule-1: Secreted
Alternative ELISA Names Vascular Cell Adhesion Protein 1 ELISA kit
V-Cam 1 ELISA kit
Vcam-1 ELISA kit
Cd Antigen Cd106 Cleaved Into - Soluble Vascular Cell Adhesion Molecule-1 ELISA kit
Vcam1 ELISA kit
Vcam-1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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