產(chǎn)品詳情
簡單介紹:
Anti-Fascin antibody (Full length) [ZM192] (STJ180352)
詳情介紹:
Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-Fascin (Full length) is suitable for use in Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | ZM192 |
Conjugation: | Unconjugated |
Isotype: | IgG2a/Kappa |
Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% proclin<="" td=""> 0.1%> |
Purification: | Affinity purified |
Dilution Range: | 1:100‐200 |
Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Gene Symbol: | FSCN1 |
Gene ID: | 6624 |
Uniprot ID: | FSCN1_HUMAN |
Immunogen Region: | Full length |
Specificity: | Positive control: Hodgkin's lymphoma or spleen |
Immunogen: | Full length recombinant human FSCN1 protein |
Tissue Specificity | Ubiquitous. |
Post Translational Modifications | Phosphorylation at Ser-39 inhibits actin-binding. Phosphorylation is required for the reorganization of the actin cytoskeleton in response to NGF. |
Function | Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF. |
Protein Name | Fascin 55 Kda Actin-Bundling Protein Singed-Like Protein P55 |
Database Links | Reactome: R-HSA-6785807 |
Cellular Localisation | Cytoplasm Cytosol Cell Cortex Cytoskeleton Stress Fiber Cell Projection Filopodium Invadopodium Microvillus Cell Junction Colocalized With Rufy3 And F-Actin At Filipodia Of The Axonal Growth Cone Colocalized With Dbn1 And F-Actin At The Transitional Domain Of The Axonal Growth Cone |
Alternative Antibody Names | Anti-Fascin antibody Anti-55 Kda Actin-Bundling Protein antibody Anti-Singed-Like Protein antibody Anti-P55 antibody Anti-FSCN1 antibody Anti-FAN1 antibody Anti-HSN antibody Anti-SNL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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