產(chǎn)品詳情
簡單介紹：
Anti-FANCC antibody (340-558) (STJ23623)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FANCC (340-558) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FANCC |
| Gene ID: | 2176 |
| Uniprot ID: | FANCC_HUMAN |
| Immunogen Region: | 340-558 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-558 of human FANCC (NP_000127.2). |
| Immunogen Sequence: | YFPYTSPSLAMVLLQDPQDI PRGHWLQTLKHISELLREAV EDQTHGSCGGPFESWFLFIH FGGWAEMVAEQLLMSAAEPP TALLWLLAFYYGPRDGRQQR AQTMVQVKAVLGHLLAMSRS SSLSAQDLQTVAGQGTDTDL RAPAQQLIRHLLLNFLLWAP GGHTIAWDVITLMAHTAEIT HEIIGFLDQTLYRWNRLGIE SPRSEKLARELLKELRTQV |
| Tissue Specificity | Ubiquitous. |
| Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. |
| Protein Name | Fanconi Anemia Group C Protein Protein Facc |
| Database Links | Reactome: R-HSA-6783310 Reactome: R-HSA-6796648 |
| Cellular Localisation | Nucleus Cytoplasm The Major Form Is Nuclear The Minor Form Is Cytoplasmic |
| Alternative Antibody Names | Anti-Fanconi Anemia Group C Protein antibody Anti-Protein Facc antibody Anti-FANCC antibody Anti-FAC antibody Anti-FACC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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