產(chǎn)品詳情
簡單介紹：
Anti-F9 antibody (29-461) (STJ23601)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Factor IX/F9 (29-461) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | F9 |
| Gene ID: | 2158 |
| Uniprot ID: | FA9_HUMAN |
| Immunogen Region: | 29-461 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-461 of human Factor IX/F9 (NP_000124.1). |
| Immunogen Sequence: | TVFLDHENANKILNRPKRYN SGKLEEFVQGNLERECMEEK CSFEEAREVFENTERTTEFW KQYVDGDQCESNPCLNGGSC KDDINSYECWCPFGFEGKNC ELDVTCNIKNGRCEQFCKNS ADNKVVCSCTEGYRLAENQK SCEPAVPFPCGRVSVSQTSK LTRA |
| Tissue Specificity | Detected in blood plasma (at protein level). Synthesized primarily in the liver and secreted in plasma. |
| Post Translational Modifications | Activated by factor XIa, which excises the activation peptide. The propeptide can also be removed by snake venom protease. The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. |
| Function | Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. |
| Protein Name | Coagulation Factor Ix Christmas Factor Plasma Thromboplastin Component Ptc Cleaved Into - Coagulation Factor Ixa Light Chain - Coagulation Factor Ixa Heavy Chain |
| Database Links | Reactome: R-HSA-140834 Reactome: R-HSA-140837 Reactome: R-HSA-159740 Reactome: R-HSA-159763 Reactome: R-HSA-159782 Reactome: R-HSA-9672383 Reactome: R-HSA-9672396 Reactome: R-HSA-9673202 Reactome: R-HSA-9673218 Reactome: R-HSA-9673221 Reactome: R-HSA-9673240 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Coagulation Factor Ix antibody Anti-Christmas Factor antibody Anti-Plasma Thromboplastin Component antibody Anti-Ptc Cleaved Into - Coagulation Factor Ixa Light Chain - Coagulation Factor Ixa Heavy Chain antibody Anti-F9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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