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產(chǎn)品詳情

  • 產(chǎn)品名稱：Mouse TGM3 (Transglutaminase 3, Epidermal) Sandwich ELISA Kit (STJE0012543)

  • 產(chǎn)品型號：STJE0012543
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡單介紹：
Mouse TGM3 (Transglutaminase 3, Epidermal) Sandwich ELISA Kit (STJE0012543)
詳情介紹：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.255ng/mL
Detection Limit: 0.625-40ng/mL
Short Description: This TGM3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Tgm3
Gene ID: 21818
Uniprot ID: TGM3_MOUSE
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in skin and stomach and, at lower levels, in testis, kidney and spleen (at protein level). On the basis of its catalytic activity, detected in the epidermis, around the granular and spinous layers but not in the outermost cornified layers. In hair follicles, mainly located in the medulla and the hair cortex.
Post Translational Modifications Activated by proteolytic processing. In vitro activation is commonly achieved by cleavage with dispase, a neutral bacterial protease. Physiological activation may be catalyzed by CTSL and, to a lesser extent, by CTSS.
Function Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold. In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
Protein Name Protein-Glutamine Gamma-Glutamyltransferase E
Transglutaminase E
Tg(E
Tge
Tgase E
Transglutaminase-3
Tgase-3 Cleaved Into - Protein-Glutamine Gamma-Glutamyltransferase E 50 Kda Catalytic Chain - Protein-Glutamine Gamma-Glutamyltransferase E 27 Kda Non-Catalytic Chain
Database Links
Cellular Localisation Cytoplasm
Alternative ELISA Names Protein-Glutamine Gamma-Glutamyltransferase E ELISA kit
Transglutaminase E ELISA kit
Tg(E ELISA kit
Tge ELISA kit
Tgase E ELISA kit
Transglutaminase-3 ELISA kit
Tgase-3 Cleaved Into - Protein-Glutamine Gamma-Glutamyltransferase E 50 Kda Catalytic Chain - Protein-Glutamine Gamma-Glutamyltransferase E 27 Kda Non-Catalytic Chain ELISA kit
Tgm3 ELISA kit
Tgase3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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