產(chǎn)品詳情
簡單介紹：
Anti-EXOC1 antibody (645-894) (STJ116329)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-EXOC1 (645-894) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EXOC1 |
| Gene ID: | 55763 |
| Uniprot ID: | EXOC1_HUMAN |
| Immunogen Region: | 645-894 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 645-894 of human EXOC1 (NP_001020095.1). |
| Immunogen Sequence: | RNFDKCISNQIRQMEEVKIS KKSKVGILPFVAEFEEFAGL AESIFKNAERRGDLDKAYTK LIRGVFVNVEKVANESQKTP RDVVMMENFHHIFATLSRLK ISCLEAEKKEAKQKYTDHLQ SYVIYSLGQPLEKLNHFFEG VEARVAQGIREEEVSYQLAF NKQELRKVIKEYPGKEVKKG LDNLYKKVDKHLCEEENLLQ VVWHSMQDEFIRQYKHFEGL IARCYPGSGVTMEFTIQDI |
| Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (Microbial infection) Has an antiviral effect against flaviviruses by affecting viral RNA transcription and translation through the sequestration of elongation factor 1-alpha (EEF1A1). This results in decreased viral RNA synthesis and decreased viral protein translation. |
| Protein Name | Exocyst Complex Component 1 Exocyst Complex Component Sec3 |
| Database Links | Reactome: R-HSA-1445148 Reactome: R-HSA-264876 Reactome: R-HSA-5620916 |
| Cellular Localisation | Midbody Midbody Ring Cytoplasm Perinuclear Region Cell Membrane Colocalizes With Cntrl/Centriolin At The Midbody Ring Localizes In Cell Membrane In The Presence Of Slc6a9 |
| Alternative Antibody Names | Anti-Exocyst Complex Component 1 antibody Anti-Exocyst Complex Component Sec3 antibody Anti-EXOC1 antibody Anti-SEC3 antibody Anti-SEC3L1 antibody Anti-BM-012 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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