產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-EVC antibody (743-992) (STJ114509)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-EVC (743-992) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:1000-1:3000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | EVC |
Gene ID: | 2121 |
Uniprot ID: | EVC_HUMAN |
Immunogen Region: | 743-992 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 743-992 of human EVC (NP_714928.1). |
Immunogen Sequence: | AIGQALLVHARNAATKSRAK DRDDFKRTLMEAAVESVYVT SAGVSRLVQAYYQQIGRIME DHEERKLQHLKTLQGERMEN YKLRKKQELSNPSSGSRTAG GAHETSQAVHQRMLSQQKRF LAQFPVHQQMRLHAQQQQAG VMDLLEAQLETQLQEAEQNF ISELAALARVPLAESKLLPA KRGLLEKPLRTKRKKPLPQE RGDLGVPNNEDLASGDQTSG SLSSKRLSQQESEAGDSGN |
Tissue Specificity | Found in the developing vertebral bodies, ribs, upper and lower limbs, heart, kidney, lung. |
Function | Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Involved in endochondral growth and skeletal development. |
Protein Name | Evc Complex Member Evc Dwf-1 Ellis-Van Creveld Syndrome Protein |
Database Links | Reactome: R-HSA-5632684 Reactome: R-HSA-5635838 |
Cellular Localisation | Cell Membrane Single-Pass Membrane Protein Cytoplasm Cytoskeleton Cilium Basal Body Cell Projection Cilium Cilium Membrane Evc2 Is Required For The Localization Of Evc At The Base Of Primary Cilia The Evc Complex Localizes At The Base Of Cilia In The Evc Zone Of Primary Cilia In A Efcab7-Dependent Manner |
Alternative Antibody Names | Anti-Evc Complex Member Evc antibody Anti-Dwf-1 antibody Anti-Ellis-Van Creveld Syndrome Protein antibody Anti-EVC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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