產(chǎn)品詳情
簡單介紹：
Anti-ETFB antibody (80-230) (STJ118483)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-ETFB (80-230) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ETFB |
| Gene ID: | 2109 |
| Uniprot ID: | ETFB_HUMAN |
| Immunogen Region: | 80-230 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-230 of human ETFB (NP_001976.1). |
| Immunogen Sequence: | AMGADRGIHVEVPPAEAERL GPLQVARVLAKLAEKEKVDL VLLGKQAIDDDCNQTGQMTA GFLDWPQGTFASQVTLEGDK LKVEREIDGGLETLRLKLPA VVTADLRLNEPRYATLPNIM KAKKKKIEVIKPGDLGVDLT SKLSVISVEDP |
| Tissue Specificity | Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas. |
| Post Translational Modifications | Methylated. Trimethylation at Lys-200 and Lys-203 may negatively regulate the activity in electron transfer from acyl-CoA dehydrogenases. |
| Function | Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role. |
| Protein Name | Electron Transfer Flavoprotein Subunit Beta Beta-Etf |
| Database Links | Reactome: R-HSA-611105 Reactome: R-HSA-8876725 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Electron Transfer Flavoprotein Subunit Beta antibody Anti-Beta-Etf antibody Anti-ETFB antibody Anti-FP585 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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