產品詳情
簡單介紹:
Anti-ESYT2 antibody (STJA0008736)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Extended synaptotagmin-2 is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ESYT2 |
Gene ID: | 57488 |
Uniprot ID: | ESYT2_HUMAN |
Specificity: | This antibody detects endogenous levels of FAM62B at Human, Mouse |
Immunogen: | Synthesized peptide derived from human FAM62B |
Function | Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding.this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS). |
Protein Name | Extended Synaptotagmin-2 E-Syt2 Chr2syt |
Database Links | Reactome: R-HSA-1660662 |
Cellular Localisation | Cell Membrane Peripheral Membrane Protein Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Localizes To Endoplasmic Reticulum-Plasma Membrane Contact Sites (Epcs) Recruited To The Cell Membrane Via The Third C2 Domain |
Alternative Antibody Names | Anti-Extended Synaptotagmin-2 antibody Anti-E-Syt2 antibody Anti-Chr2syt antibody Anti-ESYT2 antibody Anti-FAM62B antibody Anti-KIAA1228 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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