產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-ESYT2 antibody (630-760) (STJ114699)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FAM62B (630-760) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ESYT2 |
| Gene ID: | 57488 |
| Uniprot ID: | ESYT2_HUMAN |
| Immunogen Region: | 630-760 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1). |
| Immunogen Sequence: | EKRERPPDHQHSAQVKRPSV SKEGRKTSIKSHMSGSPGPG GSNTAPSTPVIGGSDKPGME EKAQPPEAGPQGLHDLGRSS SSLLASPGHISVKEPTPSIA SDISLPIATQELRQRLRQLE NGTTLGQSPLG |
| Tissue Specificity | Widely expressed with high level in cerebellum. |
| Function | Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding.this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS). |
| Protein Name | Extended Synaptotagmin-2 E-Syt2 Chr2syt |
| Database Links | Reactome: R-HSA-1660662 |
| Cellular Localisation | Cell Membrane Peripheral Membrane Protein Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Localizes To Endoplasmic Reticulum-Plasma Membrane Contact Sites (Epcs) Recruited To The Cell Membrane Via The Third C2 Domain |
| Alternative Antibody Names | Anti-Extended Synaptotagmin-2 antibody Anti-E-Syt2 antibody Anti-Chr2syt antibody Anti-ESYT2 antibody Anti-FAM62B antibody Anti-KIAA1228 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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