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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-ESYT1 antibody (90-220) (STJ117605)

  • 產(chǎn)品型號(hào)：STJ117605
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-ESYT1 antibody (90-220) (STJ117605)
詳情介紹：
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ESYT1 (90-220) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ESYT1
Gene ID: 23344
Uniprot ID: ESYT1_HUMAN
Immunogen Region: 90-220
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-220 of human ESYT1 (NP_056107.1).
Immunogen Sequence: GWRRVRDEKERSLRAARQLL DDEEQLTAKTLYMSHRELPA WVSFPDVEKAEWLNKIVAQV WPFLGQYMEKLLAETVAPAV RGSNPHLQTFTFTRVELGEK PLRIIGVKVHPGQRKEQILL DLNISYVGDVQ
Tissue Specificity Widely expressed.
Post Translational Modifications Phosphorylated on Ser residues in insulin-treated adipocytes (in vitro).this promotes interaction with SLC2A4.
Function Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.
Protein Name Extended Synaptotagmin-1
E-Syt1
Membrane-Bound C2 Domain-Containing Protein
Database Links Reactome: R-HSA-1660662
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013405
Reactome: R-HSA-9013408
Reactome: R-HSA-9013423
Reactome: R-HSA-9035034
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Cell Membrane
Peripheral Membrane Protein
Localizes Primarily To The Endoplasmic Reticulum
Recruited To Sites Of Contact Between The Endoplasmic Reticulum And The Cell Membrane In Response To Increased Cytosolic Calcium Levels
Alternative Antibody Names Anti-Extended Synaptotagmin-1 antibody
Anti-E-Syt1 antibody
Anti-Membrane-Bound C2 Domain-Containing Protein antibody
Anti-ESYT1 antibody
Anti-FAM62A antibody
Anti-KIAA0747 antibody
Anti-MBC2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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