產(chǎn)品詳情
簡單介紹:
Mouse SIAL2 (Sialidase 2, Cytosolic) Sandwich ELISA Kit Ready-To-Use (STJE0018547)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.085ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This SIAL2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Neu2 |
Gene ID: | 23956 |
Uniprot ID: | NEUR2_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Highly expressed in heart. |
Post Translational Modifications | |
Function | Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Recognizes sialyl linkage positions of the glycan moiety as well as the supramolecular organization of the sialoglycoconjugate. Displays preference for alpha-(2->3)-sialylated GD1a and GT1B gangliosides over alpha-(2->8)-sialylated GD1b, in both monomeric forms and micelles. Hydrolyzes exclusively monomeric GM1 ganglioside, but has no activity toward the miscellar form. Has lower sialidase activity for glycoproteins such as fetuin and TF/transferrin that carry a mixture of alpha-(2->3) and alpha-(2->6)-sialyl linkages. Cleaves milk oligosaccharide alpha-(2->3)-sialyllactose, but is inactive toward isomer alpha-(2->6)-sialyllactose isomer. Has no activity toward colominic acid, a homomer of alpha-(2->8)-linked Neu5Ac residues. |
Protein Name | Sialidase-2 Cytosolic Sialidase Mouse Skeletal Muscle Sialidase Mss Murine Thymic Sialidase Mts N-Acetyl-Alpha-Neuraminidase 2 |
Database Links | Reactome: R-MMU-1660662 Reactome: -MMU-4085001 |
Cellular Localisation | Cytoplasm Cytosol |
Alternative ELISA Names | Sialidase-2 ELISA kit Cytosolic Sialidase ELISA kit Mouse Skeletal Muscle Sialidase ELISA kit Mss ELISA kit Murine Thymic Sialidase ELISA kit Mts ELISA kit N-Acetyl-Alpha-Neuraminidase 2 ELISA kit Neu2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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