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產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Mouse SIAL2 (Sialidase 2, Cytosolic) Sandwich ELISA Kit (STJE0012160)

  • 產(chǎn)品型號(hào)：STJE0012160
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Mouse SIAL2 (Sialidase 2, Cytosolic) Sandwich ELISA Kit (STJE0012160)
詳情介紹：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.085ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This SIAL2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Neu2
Gene ID: 23956
Uniprot ID: NEUR2_MOUSE
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in heart.
Post Translational Modifications
Function Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Recognizes sialyl linkage positions of the glycan moiety as well as the supramolecular organization of the sialoglycoconjugate. Displays preference for alpha-(2->3)-sialylated GD1a and GT1B gangliosides over alpha-(2->8)-sialylated GD1b, in both monomeric forms and micelles. Hydrolyzes exclusively monomeric GM1 ganglioside, but has no activity toward the miscellar form. Has lower sialidase activity for glycoproteins such as fetuin and TF/transferrin that carry a mixture of alpha-(2->3) and alpha-(2->6)-sialyl linkages. Cleaves milk oligosaccharide alpha-(2->3)-sialyllactose, but is inactive toward isomer alpha-(2->6)-sialyllactose isomer. Has no activity toward colominic acid, a homomer of alpha-(2->8)-linked Neu5Ac residues.
Protein Name Sialidase-2
Cytosolic Sialidase
Mouse Skeletal Muscle Sialidase
Mss
Murine Thymic Sialidase
Mts
N-Acetyl-Alpha-Neuraminidase 2
Database Links Reactome: R-MMU-1660662
Reactome: -MMU-4085001
Cellular Localisation Cytoplasm
Cytosol
Alternative ELISA Names Sialidase-2 ELISA kit
Cytosolic Sialidase ELISA kit
Mouse Skeletal Muscle Sialidase ELISA kit
Mss ELISA kit
Murine Thymic Sialidase ELISA kit
Mts ELISA kit
N-Acetyl-Alpha-Neuraminidase 2 ELISA kit
Neu2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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