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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-CD8 antibody [MEM-31] (STJ16100051)

  • 產(chǎn)品型號：STJ16100051-01
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡單介紹：
Anti-CD8 antibody [MEM-31] (STJ16100051)
詳情介紹：
Host: Mouse
Applications: FC/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD8 is suitable for use in Flow Cytometry and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: MEM-31
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration: 1 mg/mL
Dilution Range: FC 1 μg/ml-IP-Mass Cytometry
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Crude thymus membrane fraction.
Background The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as alpha/beta heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as alpha/alpha homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha-beta but not alpha-alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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