產(chǎn)品詳情
簡單介紹：
Anti-ERF antibody (492-541 aa) (STJ92983)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-ETS domain-containing transcription factor ERF (492-541 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ERF |
| Gene ID: | 2077 |
| Uniprot ID: | ERF_HUMAN |
| Immunogen Region: | 492-541 aa |
| Specificity: | ERF Polyclonal Antibody detects endogenous levels of ERF protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ERF at the amino acid range 492-541 |
| Post Translational Modifications | Phosphorylated by multiple kinases including MAPK1/ERK2 at THR-526. Phosphorylation regulates the activity of ERF. |
| Function | Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment. May be important for regulating trophoblast stem cell differentiation. |
| Protein Name | Ets Domain-Containing Transcription Factor Erf Ets2 Repressor Factor Pe-2 |
| Database Links | Reactome: R-HSA-2559585 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ets Domain-Containing Transcription Factor Erf antibody Anti-Ets2 Repressor Factor antibody Anti-Pe-2 antibody Anti-ERF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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