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產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Anti-ERCC1 antibody (1-100 aa) (STJ196164)

  • 產(chǎn)品型號(hào)：STJ196164
  • 產(chǎn)品廠(chǎng)商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Anti-ERCC1 antibody (1-100 aa) (STJ196164)
詳情介紹：
Host: Mouse
Applications: WB/IF/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-DNA excision repair protein ERCC-1 (1-100 aa) is suitable for use in Western Blot, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: WB 1:500-2000
IHC 1:100-300
IF 1:100-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERCC1
Gene ID: 2067
Uniprot ID: ERCC1_HUMAN
Immunogen Region: 1-100 aa
Specificity: This antibody detects endogenous levels of human ERCC1
Immunogen: Synthesized peptide derived from the human ERCC1 at the amino acid range 1-100
Function Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. Isoform 2: Not functional in the nucleotide excision repair pathway. Isoform 3: Not functional in the nucleotide excision repair pathway. Isoform 4: Not functional in the nucleotide excision repair pathway.
Protein Name Dna Excision Repair Protein Ercc-1
Database Links Reactome: R-HSA-5685938
Reactome: R-HSA-5696395
Reactome: R-HSA-5696400
Reactome: R-HSA-6782135
Reactome: R-HSA-6783310
Cellular Localisation Isoform 1: Nucleus
Isoform 2: Cytoplasm
Nucleus
Isoform 3: Nucleus
Isoform 4: Nucleus
Alternative Antibody Names Anti-Dna Excision Repair Protein Ercc-1 antibody
Anti-ERCC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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