產(chǎn)品詳情
簡單介紹：
Anti-ERBB2IP antibody (1152-1371) (STJ111318)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-ERBB2IP (1152-1371) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ERBIN |
| Gene ID: | 55914 |
| Uniprot ID: | ERBIN_HUMAN |
| Immunogen Region: | 1152-1371 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165.1). |
| Immunogen Sequence: | IPERTMSVSDFNYSRTSPSK RPNARVGSEHSLLDPPGKSK VPRDWREQVLRHIEAKKLEK MPLSNGQMGQPLRPQANYSQ IHHPPQASVARHPSREQLID YLMLKVAHQPPYTQPHCSPR QGHELAKQEIRVRVEKDPEL GFSISGGVGGRGNPFRPDDD GIFVTRVQPEGPASKLLQPG DKIIQANGYSFINIEHGQAV SLLKTFQNTVELIIVREVSS |
| Tissue Specificity | Highly expressed in brain, heart, kidney, muscle and stomach, followed by liver, spleen and intestine. |
| Function | Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state. Inhibits NOD2-dependent NF-kappa-B signaling and pro-inflammatory cytokine secretion. |
| Protein Name | Erbin Densin-180-Like Protein Erbb2-Interacting Protein Protein Lap2 |
| Database Links | Reactome: R-HSA-1227986 Reactome: R-HSA-8863795 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 Reactome: R-HSA-9013149 Reactome: R-HSA-9013404 Reactome: R-HSA-9013408 Reactome: R-HSA-9013423 Reactome: R-HSA-9634285 Reactome: R-HSA-9652282 Reactome: R-HSA-9664565 Reactome: R-HSA-9665233 Reactome: R-HSA-9665244 Reactome: R-HSA-9665245 Reactome: R-HSA-9665246 Reactome: R-HSA-9665247 Reactome: R-HSA-9665249 Reactome: R-HSA-9665250 Reactome: R-HSA-9665251 Reactome: R-HSA-9665348 Reactome: R-HSA-9665686 Reactome: R-HSA-9665737 |
| Cellular Localisation | Cell Junction Hemidesmosome Nucleus Membrane Basolateral Cell Membrane Found In Hemidesmosomes Which Are Cell-Substrate Adhesion Complexes In Stratified Epithelia In Transfected Cells Either Diffusely Distributed Over The Cytoplasm Or Concentrated At The Basolateral Membrane Colocalizes With The Adrenergic Receptors Adren1a And Adren1b At The Nuclear Membrane Of Cardiac Myocytes |
| Alternative Antibody Names | Anti-Erbin antibody Anti-Densin-180-Like Protein antibody Anti-Erbb2-Interacting Protein antibody Anti-Protein Lap2 antibody Anti-ERBIN antibody Anti-ERBB2IP antibody Anti-KIAA1225 antibody Anti-LAP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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