產(chǎn)品詳情
簡單介紹：
Mouse RHO (Rhodopsin) Sandwich ELISA Kit Ready-To-Use (STJE0018273)
詳情介紹：
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.056ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This RHO Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | Rho |
| Gene ID: | 212541 |
| Uniprot ID: | OPSD_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Rod-shaped photoreceptor cells in the retina (at protein level). |
| Post Translational Modifications | Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region. Contains one covalently linked retinal chromophore. Upon light absorption, the covalently bound 11-cis-retinal is converted to all-trans-retinal. After hydrolysis of the Schiff base and release of the covalently bound all-trans-retinal, active rhodopsin is regenerated by binding of a fresh molecule of 11-cis-retinal. |
| Function | Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling. |
| Protein Name | Rhodopsin |
| Database Links | Reactome: R-MMU-2453902 Reactome: -MMU-2485179 Reactome: -MMU-2514859 Reactome: -MMU-418594 Reactome: -MMU-419771 Reactome: -MMU-5620916 |
| Cellular Localisation | Membrane Multi-Pass Membrane Protein Cell Projection Cilium Photoreceptor Outer Segment Synthesized In The Inner Segment (Is) Of Rod Photoreceptor Cells Before Vectorial Transport To Disk Membranes In The Rod Outer Segment (Os) Photosensory Cilia |
| Alternative ELISA Names | Rhodopsin ELISA kit Rho ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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