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產(chǎn)品詳情

  • 產(chǎn)品名稱：Mouse REG3a (Regenerating Islet Derived Protein 3 Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0018241)

  • 產(chǎn)品型號(hào)：STJE0018241
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Mouse REG3a (Regenerating Islet Derived Protein 3 Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0018241)
詳情介紹：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 6.3pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This REG3a Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Reg3a
Gene ID: 19694
Uniprot ID: REG3A_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Small intestine and pancreas.
Post Translational Modifications Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity.
Function Bactericidal C-type lectin. The lack of the EPN motif may explain its inability to bind peptidoglycan. Acts as a hormone in response to different stimuli like anti-inflammatory signals, such as IL17A, or gut microbiome. Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways. Induced by IL17A in keratinocytes, regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. In parallel, inhibits skin inflammation through the inhibition of inflammatory cytokines such as IL6 and TNF. In pancreas, is able to permealize beta-cells membrane and stimulate their proliferation.
Protein Name Regenerating Islet-Derived Protein 3-Alpha
Reg-3-Alpha
Islet Of Langerhans Regenerating Protein 3
Lithostathine 3
Pancreatitis-Associated Protein 2
Regenerating Islet-Derived Protein Iii-Alpha
Reg Iii-Alpha Cleaved Into - Regenerating Islet-Derived Protein 3-Alpha 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Alpha 15 Kda Form
Database Links Reactome: R-MMU-6803157
Cellular Localisation Secreted
Found In The Apical Region Of Pancreatic Acinar Cells
Alternative ELISA Names Regenerating Islet-Derived Protein 3-Alpha ELISA kit
Reg-3-Alpha ELISA kit
Islet Of Langerhans Regenerating Protein 3 ELISA kit
Lithostathine 3 ELISA kit
Pancreatitis-Associated Protein 2 ELISA kit
Regenerating Islet-Derived Protein Iii-Alpha ELISA kit
Reg Iii-Alpha Cleaved Into - Regenerating Islet-Derived Protein 3-Alpha 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Alpha 15 Kda Form ELISA kit
Reg3a ELISA kit
Pap2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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