產(chǎn)品詳情
簡單介紹：
Anti-CD68 antibody (Internal) (STJ73443)
詳情介紹：
| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-CD68 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | WB-1-3μg/ml ELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CD68 |
| Gene ID: | 968 |
| Uniprot ID: | CD68_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001242.2; NP_001035148.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_001242.2; NP_001035148.1). |
| Immunogen Sequence: | PNKTKVQGSCEGAH |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
| Protein Name | Macrosialin Gp110 Cd Antigen Cd68 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform Short: Cell Membrane Single-Pass Type I Membrane Protein Isoform Long: Endosome Membrane Lysosome Membrane |
| Alternative Antibody Names | Anti-Macrosialin antibody Anti-Gp110 antibody Anti-Cd Antigen Cd68 antibody Anti-CD68 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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