產(chǎn)品詳情
簡單介紹：
Anti-CD68 antibody (240-290) {FITC} (STJ500482)
詳情介紹：
| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-CD68 (240-290) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | FITC |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Concentration: | 0.5-1.5 μg/μl |
| Dilution Range: | WB: 1:2, 500-1:5, 000 ELISA: 1:50, 000 IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Cd68 |
| Gene ID: | 12514 |
| Uniprot ID: | CD68_MOUSE |
| Immunogen Region: | 240-290 |
| Immunogen: | Synthetic peptide taken within amino acid region 240-290 on mouse CD68/Macrosialin protein. |
| Tissue Specificity | Expressed in tissue macrophages and to a lesser extent in dendritic cells. |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
| Protein Name | Macrosialin Cd Antigen Cd68 |
| Database Links | Reactome: R-MMU-6798695 |
| Cellular Localisation | Isoform Long: Endosome Membrane Single-Pass Type I Membrane Protein Lysosome Membrane Isoform Short: Cell Membrane |
| Alternative Antibody Names | Anti-Macrosialin antibody Anti-Cd Antigen Cd68 antibody Anti-Cd68 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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