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產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Mouse PRDX6 (Peroxiredoxin 6) Sandwich ELISA Kit (STJE0011651)

  • 產(chǎn)品型號(hào)：STJE0011651
  • 產(chǎn)品廠(chǎng)商：ST john's laboratory
  • 產(chǎn)品文檔：
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Mouse PRDX6 (Peroxiredoxin 6) Sandwich ELISA Kit (STJE0011651)
詳情介紹：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.063ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This PRDX6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Prdx6
Gene ID: 11758
Uniprot ID: PRDX6_MOUSE
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in heart, kidney and liver. Moderate expression in brain and stomach. Very low levels in intestine.
Post Translational Modifications Irreversibly inactivated by overoxidation of Cys-47 to sulfinic acid (Cys-SO(2)H) and sulfonic acid (Cys-SO(3)H) forms upon oxidative stress. Phosphorylation at Thr-177 by MAP kinases increases the phospholipase activity of the enzyme. The phosphorylated form exhibits a greater lysophosphatidylcholine acyltransferase activity compared to the non-phosphorylated form.
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Has phospholipase activity. Can either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis. Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate.
Protein Name Peroxiredoxin-6
1-Cys Peroxiredoxin
1-Cys Prx
Acidic Calcium-Independent Phospholipase A2
Aipla2
Antioxidant Protein 2
Glutathione-Dependent Peroxiredoxin
Lysophosphatidylcholine Acyltransferase 5
Lpc Acyltransferase 5
Lpcat-5
Lyso-Pc Acyltransferase 5
Non-Selenium Glutathione Peroxidase
Nsgpx
Database Links Reactome: R-MMU-3299685
Reactome: -MMU-6798695
Cellular Localisation Cytoplasm
Lysosome
Also Found In Lung Secretory Organelles (Lamellar Bodies)
Alternative ELISA Names Peroxiredoxin-6 ELISA kit
1-Cys Peroxiredoxin ELISA kit
1-Cys Prx ELISA kit
Acidic Calcium-Independent Phospholipase A2 ELISA kit
Aipla2 ELISA kit
Antioxidant Protein 2 ELISA kit
Glutathione-Dependent Peroxiredoxin ELISA kit
Lysophosphatidylcholine Acyltransferase 5 ELISA kit
Lpc Acyltransferase 5 ELISA kit
Lpcat-5 ELISA kit
Lyso-Pc Acyltransferase 5 ELISA kit
Non-Selenium Glutathione Peroxidase ELISA kit
Nsgpx ELISA kit
Prdx6 ELISA kit
Aop2 ELISA kit
Ltw4 ELISA kit
Prdx5 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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