產(chǎn)品詳情
簡單介紹：
Anti-CD66c/d antibody (31-80 aa) (STJ97289)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Carcinoembryonic antigen-related cell adhesion molecule 3 and Carcinoembryonic antigen-related cell adhesion molecule 6 (31-80 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CEACAM6 CEACAM3 |
| Gene ID: | 4680 1084 |
| Uniprot ID: | CEAM6_HUMAN CEAM3_HUMAN |
| Immunogen Region: | 31-80 aa |
| Specificity: | CD66c/d Polyclonal Antibody detects endogenous levels of CD66c/d protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human CEACAM3/CEACAM6 at the amino acid range 31-80 |
| Post Translational Modifications | Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected. |
| Function | Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. |
| Protein Name | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 Carcinoembryonic Antigen Cgm1 Cd Antigen Cd66d |
| Database Links | Reactome: R-HSA-202733 Reactome: R-HSA-6798695 |
| Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 antibody Anti-Carcinoembryonic Antigen Cgm1 antibody Anti-Cd Antigen Cd66d antibody Anti-CEACAM3 antibody Anti-CD66D antibody Anti-CGM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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