產(chǎn)品詳情
簡單介紹：
Anti-EPC1 antibody (1-300) (STJ28370)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-EPC1 (1-300) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EPC1 |
| Gene ID: | 80314 |
| Uniprot ID: | EPC1_HUMAN |
| Immunogen Region: | 1-300 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EPC1 (NP_079485.1). |
| Immunogen Sequence: | MSKLSFRARALDASKPLPVF RCEDLPDLHEYASINRAVPQ MPTGMEKEEESEHHLQRAIS AQQVYGEKRDNMVIPVPEAE SNIAYYESIYPGEFKMPKQL IHIQPFSLDAEQPDYDLDSE DEVFVNKLKKKMDICPLQFE EMIDRLEKGSGQQPVSLQEA KLLLKEDDELIREVYEYWIK KRKNCRGPSLIPSVKQEKRD GSSTNDPYVAFRRRTEKMQT RKNRKNDEASYEKMLKLRR |
| Function | Component of the NuA4 histone acetyltransferase (HAT) complex, a multiprotein complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) by promoting homologous recombination (HR). The NuA4 complex is also required for spermatid development by promoting acetylation of histones: histone acetylation is required for histone replacement during the transition from round to elongating spermatids. In the NuA4 complex, EPC1 is required to recruit MBTD1 into the complex. |
| Protein Name | Enhancer Of Polycomb Homolog 1 |
| Database Links | Reactome: R-HSA-3214847 Reactome: R-HSA-8953750 |
| Cellular Localisation | Nucleus Cytoplasm |
| Alternative Antibody Names | Anti-Enhancer Of Polycomb Homolog 1 antibody Anti-EPC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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