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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-EP400 antibody (90-330) (STJ114044)

  • 產(chǎn)品型號(hào)：STJ114044
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-EP400 antibody (90-330) (STJ114044)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EP400 (90-330) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EP400
Gene ID: 57634
Uniprot ID: EP400_HUMAN
Immunogen Region: 90-330
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-330 of human EP400 (NP_056224.3).
Immunogen Sequence: TLAPLPLPSPTSPGFQFSAQ PRRFEHGSPSYIQVTSPLSQ QVQTQSPTQPSPGPGQALQN VRAGAPGPGLGLCSSSPTGG FVDASVLVRQISLSPSSGGH FVFQDGSGLTQIAQGAQVQL QHPGTPITVRERRPSQPHTQ SGGTIHHLGPQSPAAAGGAG LQPLASPSHITTANLPPQIS SIIQGQLVQQQQVLQGPPLP RPLGFERTPGVLLPGAGGAA GFGMTSPPPPTSPSRTAVP
Tissue Specificity Ubiquitously expressed.
Function Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.
Protein Name E1a-Binding Protein P400
Cag Repeat Protein 32
Domino Homolog
Hdomino
Trinucleotide Repeat-Containing Gene 12 Protein
P400 Kda Swi2/Snf2-Related Protein
Database Links Reactome: R-HSA-2559584
Reactome: R-HSA-2559586
Reactome: R-HSA-3214847
Cellular Localisation Nucleus
Alternative Antibody Names Anti-E1a-Binding Protein P400 antibody
Anti-Cag Repeat Protein 32 antibody
Anti-Domino Homolog antibody
Anti-Hdomino antibody
Anti-Trinucleotide Repeat-Containing Gene 12 Protein antibody
Anti-P400 Kda Swi2/Snf2-Related Protein antibody
Anti-EP400 antibody
Anti-CAGH32 antibody
Anti-KIAA1498 antibody
Anti-KIAA1818 antibody
Anti-TNRC12 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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