產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-ENTPD5 antibody (STJA0009575)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Nucleoside diphosphate phosphatase ENTPD5 is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ENTPD5 |
Gene ID: | 957 |
Uniprot ID: | ENTP5_HUMAN |
Specificity: | This antibody detects endogenous levels of ENTPD5 at Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from human ENTPD5 |
Post Translational Modifications | N-glycosylated.high-mannose type. Glycosylation is not essential for enzymatic activity. |
Function | Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP. In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER. |
Protein Name | Nucleoside Diphosphate Phosphatase Entpd5 Cd39 Antigen-Like 4 Er-Udpase Ectonucleoside Triphosphate Diphosphohydrolase 5 Ntpdase 5 Guanosine-Diphosphatase Entpd5 Gdpase Entpd5 Inosine Diphosphate Phosphatase Entpd5 Nucleoside Diphosphatase Uridine-Diphosphatase Entpd5 Udpase Entpd5 |
Database Links | Reactome: R-HSA-8850843 Reactome: R-HSA-9660826 |
Cellular Localisation | Endoplasmic Reticulum Secreted |
Alternative Antibody Names | Anti-Nucleoside Diphosphate Phosphatase Entpd5 antibody Anti-Cd39 Antigen-Like 4 antibody Anti-Er-Udpase antibody Anti-Ectonucleoside Triphosphate Diphosphohydrolase 5 antibody Anti-Ntpdase 5 antibody Anti-Guanosine-Diphosphatase Entpd5 antibody Anti-Gdpase Entpd5 antibody Anti-Inosine Diphosphate Phosphatase Entpd5 antibody Anti-Nucleoside Diphosphatase antibody Anti-Uridine-Diphosphatase Entpd5 antibody Anti-Udpase Entpd5 antibody Anti-ENTPD5 antibody Anti-CD39L4 antibody Anti-PCPH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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