產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-ENPP6 antibody (91-440) (STJ114178)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ENPP6 (91-440) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ENPP6 |
Gene ID: | 133121 |
Uniprot ID: | ENPP6_HUMAN |
Immunogen Region: | 91-440 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 91-440 of human ENPP6 (NP_699174.1). |
Immunogen Sequence: | GNYMWDPTTNKSFDIGVNKD SLMPLWWNGSEPLWVTLTKA KRKVYMYYWPGCEVEILGVR PTYCLEYKNVPTDINFANAV SDALDSFKSGRADLAAIYHE RIDVEGHHYGPASPQRKDAL KAVDTVLKYMTKWIQERGLQ DRLNVIIFSDHGMTDIFWMD KVIELNKYISLNDLQQVKDR GPVVSLWPAPGKHSEIYNKL STVEHMTVYEKEAIPSRFYY KKGKFVSPLTLVADEGWFI |
Tissue Specificity | Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level). |
Function | Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids. |
Protein Name | Glycerophosphocholine Cholinephosphodiesterase Enpp6 Gpc-Cpde Choline-Specific Glycerophosphodiester Phosphodiesterase Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 E-Npp 6 Npp-6 |
Database Links | Reactome: R-HSA-6814848 |
Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor A Small Amount Of The Protein May Be Found In The Extracellular Milieu |
Alternative Antibody Names | Anti-Glycerophosphocholine Cholinephosphodiesterase Enpp6 antibody Anti-Gpc-Cpde antibody Anti-Choline-Specific Glycerophosphodiester Phosphodiesterase antibody Anti-Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 antibody Anti-E-Npp 6 antibody Anti-Npp-6 antibody Anti-ENPP6 antibody Anti-UNQ1889 antibody Anti-PRO4334 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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