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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-ENPP3 antibody (281-330 aa) (STJ96639)

  • 產(chǎn)品型號(hào)：STJ96639
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-ENPP3 antibody (281-330 aa) (STJ96639)
詳情介紹：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (281-330 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ENPP3
Gene ID: 5169
Uniprot ID: ENPP3_HUMAN
Immunogen Region: 281-330 aa
Specificity: CD203c Polyclonal Antibody detects endogenous levels of CD203c protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ENPP3 at the amino acid range 281-330
Post Translational Modifications N-glycosylated. N-glycosylation is necessary for normal transport to the cell membrane, but is not the apical targeting signal.
Function Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP. Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic cells. Has also alkaline phosphodiesterase activity.
Protein Name Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 3
E-Npp 3
Npp3
Phosphodiesterase I Beta
Pd-Ibeta
Phosphodiesterase I/Nucleotide Pyrophosphatase 3
Cd Antigen Cd203c Includes - Alkaline Phosphodiesterase I - Nucleotide Pyrophosphatase
Nppase
Nucleotide Diphosphatase
Database Links Reactome: R-HSA-199220
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Apical Cell Membrane
Secreted
Detected At The Cell Surface Of Basophils
Detected At The Apical Plasma Membrane Of Bile Duct Cells
Located To The Apical Surface In Intestinal And Kidney Epithelial Cells
Secreted In Serum
And In Lumen Of Epithelial Cells
Alternative Antibody Names Anti-Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 3 antibody
Anti-E-Npp 3 antibody
Anti-Npp3 antibody
Anti-Phosphodiesterase I Beta antibody
Anti-Pd-Ibeta antibody
Anti-Phosphodiesterase I/Nucleotide Pyrophosphatase 3 antibody
Anti-Cd Antigen Cd203c Includes - Alkaline Phosphodiesterase I - Nucleotide Pyrophosphatase antibody
Anti-Nppase antibody
Anti-Nucleotide Diphosphatase antibody
Anti-ENPP3 antibody
Anti-PDNP3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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