產(chǎn)品詳情
簡單介紹:
Anti-CD61 antibody [EBS-CD-034] (STJ16101119)
詳情介紹:
Host: | Mouse |
Applications: | FC/IF/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-CD61 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | EBS-CD-034 |
Conjugation: | Unconjugated |
Isotype: | IgMk |
Formulation: | PBS with 0.02% Sodium Azide. |
Purification: | Affinity purified from tissue culture. |
Concentration: | Can be provided as 100 μg/mL, 500 μg/mL or 1mg/mL. |
Dilution Range: | Flow cytometry (0, 5-1, 0 μg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 μg/ml). Immunohistology (1-2 μg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues has not been established to date |
Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
Immunogen: | A BALB/c mouse was immunized with stimulated human PBMC s. Fusion partner: NS-1. |
Background | EBS-CD-034 reacts with a complex of CD41 and CD61, i.e. alpha IIb integrin and the integrin beta chain. The MW of the GPIIIa is 105 kDa unreduced and 90 kDa reduced. The integrin beta 3 chain can also form a complex called the vitronectin receptor with integrin alpha V: the CD51/CD61 complex. Ligands are fibrinogen, fibronectin, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The CD51/CD61 complex is also found on endothelial cells, some B-cells, monocytes/macrophages and tumor cells. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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