產(chǎn)品詳情
簡單介紹：
Anti-EML4 antibody (360-560) (STJ118557)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-EML4 (360-560) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EML4 |
| Gene ID: | 27436 |
| Uniprot ID: | EMAL4_HUMAN |
| Immunogen Region: | 360-560 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-560 of human EML4 (NP_061936.2). |
| Immunogen Sequence: | GTFERGVGCLDFSKADSGVH LCVIDDSNEHMLTVWDWQKK AKGAEIKTTNEVVLAVEFHP TDANTIITCGKSHIFFWTWS GNSLTRKQGIFGKYEKPKFV QCLAFLGNGDVLTGDSGGVM LIWSKTTVEPTPGKGPKGVY QISKQIKAHDGSVFTLCQMR NGMLLTGGGKDRKIILWDHD LNPEREIEVPDQYGTIRAVA E |
| Post Translational Modifications | Phosphorylated during mitosis. Phosphorylation at Ser-144 and Ser-146 promotes its dissociation from microtubules during mitosis which is required for efficient chromosome congression. |
| Function | Essential for the formation and stability of microtubules (MTs). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs. Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression. |
| Protein Name | Echinoderm Microtubule-Associated Protein-Like 4 Emap-4 Restrictedly Overexpressed Proliferation-Associated Protein Ropp 120 |
| Database Links | Reactome: R-HSA-9648025 Reactome: R-HSA-9700645 Reactome: R-HSA-9725370 Reactome: R-HSA-9725371 |
| Cellular Localisation | Cytoplasm Cytoskeleton Spindle Microtubule Organizing Center Midbody Localizes To Microtubules (Mts) During Interphase With A Significantly Reduced Affinity For Mts During Mitosis |
| Alternative Antibody Names | Anti-Echinoderm Microtubule-Associated Protein-Like 4 antibody Anti-Emap-4 antibody Anti-Restrictedly Overexpressed Proliferation-Associated Protein antibody Anti-Ropp 120 antibody Anti-EML4 antibody Anti-C2orf2 antibody Anti-EMAPL4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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