產(chǎn)品詳情
簡單介紹:
Mouse PDE3B (Phosphodiesterase 3B, cGMP Inhibited) Sandwich ELISA Kit (STJE0011345)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 18.75pg/mL |
Detection Limit: | 31.2-2000pg/mL |
Short Description: | This PDE3B Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Pde3b |
Gene ID: | 18576 |
Uniprot ID: | PDE3B_MOUSE |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | Abundant in adipose tissues. |
Post Translational Modifications | Phosphorylation at Ser-273 mediates insulin-induced activation of PDE3B. |
Function | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Regulates angiogenesis by inhibiting the cAMP-dependent guanine nucleotide exchange factor RAPGEF3 and downstream phosphatidylinositol 3-kinase gamma-mediated signaling. Controls cardiac contractility by reducing cAMP concentration in cardiocytes. |
Protein Name | Cgmp-Inhibited 3' -5'-Cyclic Phosphodiesterase 3b Cgipde1 Cyclic Gmp-Inhibited Phosphodiesterase B Cgi-Pde B |
Database Links | Reactome: R-MMU-165160 Reactome: -MMU-418555 |
Cellular Localisation | Membrane Multi-Pass Membrane Protein |
Alternative ELISA Names | Cgmp-Inhibited 3' -5'-Cyclic Phosphodiesterase 3b ELISA kit Cgipde1 ELISA kit Cyclic Gmp-Inhibited Phosphodiesterase B ELISA kit Cgi-Pde B ELISA kit Pde3b ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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