產品詳情
簡單介紹:
Mouse PC (Pyruvate Carboxylase) Sandwich ELISA Kit (STJE0011296)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.117ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This PC Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | PcUniprot ID=PYC_MOUSE" |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Liver, kidney, adipose tissue, liver and brain. |
Post Translational Modifications | Acetylation of Lys-316 is observed in liver mitochondria from fasted mice but not from fed mice. Acetylation of Lys-748 might play a role in catalytic activity regulation. |
Function | Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. |
Protein Name | Pyruvate Carboxylase - Mitochondrial Pyruvic Carboxylase Pcb |
Database Links | |
Cellular Localisation | Mitochondrion Matrix |
Alternative ELISA Names | Pyruvate Carboxylase - Mitochondrial ELISA kit Pyruvic Carboxylase ELISA kit Pcb ELISA kit Pc ELISA kit Pcx ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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