產品詳情
簡單介紹:
Anti-ELOVL2 antibody (247-296) (STJ119753)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ELOVL2 (247-296) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ELOVL2 |
Gene ID: | 54898 |
Uniprot ID: | ELOV2_HUMAN |
Immunogen Region: | 247-296 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 247-296 of human ELOVL2 (NP_060240.3). |
Immunogen Sequence: | ILFLNFYVQTYRKKPMKKDM QEPPAGKEVKNGFSKAYFTA ANGVMNKKAQ |
Tissue Specificity | Liver and testis. |
Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
Protein Name | Elongation Of Very Long Chain Fatty Acids Protein 2 3-Keto Acyl-Coa Synthase Elovl2 Elovl Fatty Acid Elongase 2 Elovl Fa Elongase 2 Very Long Chain 3-Ketoacyl-Coa Synthase 2 Very Long Chain 3-Oxoacyl-Coa Synthase 2 |
Database Links | Reactome: R-HSA-2046105 Reactome: R-HSA-2046106 Reactome: R-HSA-75876 |
Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Elongation Of Very Long Chain Fatty Acids Protein 2 antibody Anti-3-Keto Acyl-Coa Synthase Elovl2 antibody Anti-Elovl Fatty Acid Elongase 2 antibody Anti-Elovl Fa Elongase 2 antibody Anti-Very Long Chain 3-Ketoacyl-Coa Synthase 2 antibody Anti-Very Long Chain 3-Oxoacyl-Coa Synthase 2 antibody Anti-ELOVL2 antibody Anti-ELG3 antibody Anti-SSC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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