產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-ELMO2 antibody (42-120) (STJ115730)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ELMO2 (42-120) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ELMO2 |
Gene ID: | 63916 |
Uniprot ID: | ELMO2_HUMAN |
Immunogen Region: | 42-120 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-120 of human ELMO2 (NP_877496.1). |
Immunogen Sequence: | SLPNPEYYTLRYADGPQLYI TEQTRSDIKNGTILQLAISP SRAARQLMERTQSSNMETRL DAMKELAKLSADVTFATEF |
Tissue Specificity | Widely expressed, with a higher expression in skeletal muscle, kidney and placenta. |
Function | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. |
Protein Name | Engulfment And Cell Motility Protein 2 Protein Ced-12 Homolog A Hced-12a |
Database Links | Reactome: R-HSA-2029482 Reactome: R-HSA-4420097 Reactome: R-HSA-8849471 Reactome: R-HSA-9013408 Reactome: R-HSA-9664422 |
Cellular Localisation | Cytoplasm Cytosol Membrane |
Alternative Antibody Names | Anti-Engulfment And Cell Motility Protein 2 antibody Anti-Protein Ced-12 Homolog A antibody Anti-Hced-12a antibody Anti-ELMO2 antibody Anti-CED12A antibody Anti-KIAA1834 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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