產(chǎn)品詳情
簡單介紹:
Mouse OX (Orexin) Sandwich ELISA Kit (STJE0011223)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 2.27pg/mL |
Detection Limit: | 7.81-500pg/mL |
Short Description: | This OX Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Hcrt |
Gene ID: | 15171 |
Uniprot ID: | OREX_MOUSE |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | Restricted to neuronal cell bodies of the dorsal and lateral hypothalamus. |
Post Translational Modifications | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
Function | Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A: Binds to orexin receptors HCRTR1/OX1R and HCRTR2/OX2R with a high affinity. Stimulates food intake. Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner. Orexin-B: Binds to orexin receptor HCRTR2/OX2R only. Stimulates food intake. Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner. |
Protein Name | Hypocretin Neuropeptide Precursor Hypocretin Hcrt Orexin Precursor Prepro-Orexin Preprohypocretin Cleaved Into - Orexin-A Hypocretin-1 Hcrt1 - Orexin-B Hypocretin-2 Hcrt2 |
Database Links | Reactome: R-MMU-389397 Reactome: -MMU-416476 |
Cellular Localisation | Rough Endoplasmic Reticulum Cytoplasmic Vesicle Synapse Associated With Perikaryal Rough Endoplasmic Reticulum As Well As Cytoplasmic Large Granular Vesicles At Synapses |
Alternative ELISA Names | Hypocretin Neuropeptide Precursor ELISA kit Hypocretin ELISA kit Hcrt ELISA kit Orexin Precursor ELISA kit Prepro-Orexin ELISA kit Preprohypocretin Cleaved Into - Orexin-A ELISA kit Hypocretin-1 ELISA kit Hcrt1 - Orexin-B ELISA kit Hypocretin-2 ELISA kit Hcrt2 ELISA kit Hcrt ELISA kit Ox ELISA kit Ppox ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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