產(chǎn)品詳情
簡(jiǎn)單介紹:
Mouse OPN (Osteopontin) Sandwich ELISA Kit Ready-To-Use (STJE0006908)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 16pg/mL |
Detection Limit: | 39-2500pg/mL |
Short Description: | This OPN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Spp1 |
Gene ID: | 20750 |
Uniprot ID: | OSTP_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Extensively phosphorylated by FAM20C in the extracellular medium at multiple sites within the S-x-E/pS motif. The phosphorylated form inhibits hydroxyapatite crystallization. Dephosphorylation via a mechanism involving ALPL/TNAP promotes hydroxyapatite crystallization. O-glycosylated. Forms covalent cross-links mediated by transglutaminase TGM2, between a glutamine and the epsilon-amino group of a lysine residue, forming homopolymers and heteropolymers, increasing its collagen binding properties. |
Function | Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. |
Protein Name | Osteopontin 2ar Bone Sialoprotein 1 Calcium Oxalate Crystal Growth Inhibitor Protein Early T-Lymphocyte Activation 1 Protein Minopontin Secreted Phosphoprotein 1 Spp-1 |
Database Links | Reactome: R-MMU-1474228 Reactome: -MMU-186797 Reactome: -MMU-216083 Reactome: -MMU-381426 Reactome: -MMU-8957275 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Osteopontin ELISA kit 2ar ELISA kit Bone Sialoprotein 1 ELISA kit Calcium Oxalate Crystal Growth Inhibitor Protein ELISA kit Early T-Lymphocyte Activation 1 Protein ELISA kit Minopontin ELISA kit Secreted Phosphoprotein 1 ELISA kit Spp-1 ELISA kit Spp1 ELISA kit Eta-1 ELISA kit Op ELISA kit Spp-1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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