產(chǎn)品詳情
簡單介紹：
Mouse NUCB2 (Nucleobindin 2) Sandwich ELISA Kit (STJE0011142)
詳情介紹：
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 12.5pg/mL |
| Detection Limit: | 31.2-2000pg/mL |
| Short Description: | This NUCB2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | Nucb2 |
| Gene ID: | 53322 |
| Uniprot ID: | NUCB2_MOUSE |
| Sample Type: | serum, plasma or other biological fluids. |
| Tissue Specificity | Found in liver, heart, thymus, muscle, intestine, kidney, lung, spleen and throughout the brain, in cerebral cortex, hippocampus, hypothalamus and medulla oblongata. Nucb2 and necdin levels were higher in postmitotic neurons. |
| Post Translational Modifications | |
| Function | Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. |
| Protein Name | Nucleobindin-2 Dna-Binding Protein Nefa Prepronesfatin Cleaved Into - Nesfatin-1 |
| Database Links | |
| Cellular Localisation | Cytoplasm Perikaryon Endoplasmic Reticulum Golgi Apparatus Nucleus Envelope Membrane Peripheral Membrane Protein Secreted In Dendrites And Perikarya Of Brain Neurons Abundant In The Er Cisternae And Nuclear Envelope But Not Detected In Golgi Mitochondria Or Nucleoplasm In Neurons In Cell Culture Cytoplasmic And Secreted Nesfatin-1: Secreted |
| Alternative ELISA Names | Nucleobindin-2 ELISA kit Dna-Binding Protein Nefa ELISA kit Prepronesfatin Cleaved Into - Nesfatin-1 ELISA kit Nucb2 ELISA kit Nefa ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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