產(chǎn)品詳情
簡單介紹：
Anti-EIF4G3 antibody (1000-1200) (STJ116828)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-EIF4G3 (1000-1200) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EIF4G3 |
| Gene ID: | 8672 |
| Uniprot ID: | IF4G3_HUMAN |
| Immunogen Region: | 1000-1200 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human EIF4G3 (NP_003751.2). |
| Immunogen Sequence: | HKEAKIEEQEEQRKVQQLMT KEKRRPGVQRVDEGGWNTVQ GAKNSRVLDPSKFLKITKPT IDEKIQLVPKAQLGSWGKGS SGGAKASETDALRSSASSLN RFSALQPPAPSGSTPSTPVE FDSRRTLTSRGSMGREKNDK PLPSATARPNTFMRGGSSKD LLDNQSQEEQRREMLETVKQ LTGGVDVERNSTEAERNKTR E |
| Post Translational Modifications | Following infection by certain enteroviruses, rhinoviruses and aphthoviruses, EIF4G1 is cleaved by the viral protease 2A, or the leader protease in the case of aphthoviruses. This shuts down the capped cellular mRNA transcription. |
| Function | Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Functional homolog of EIF4G1. |
| Protein Name | Eukaryotic Translation Initiation Factor 4 Gamma 3 Eif-4-Gamma 3 Eif-4g 3 Eif4g 3 Eif-4-Gamma Ii Eif4gii |
| Database Links | Reactome: R-HSA-1169408 |
| Alternative Antibody Names | Anti-Eukaryotic Translation Initiation Factor 4 Gamma 3 antibody Anti-Eif-4-Gamma 3 antibody Anti-Eif-4g 3 antibody Anti-Eif4g 3 antibody Anti-Eif-4-Gamma Ii antibody Anti-Eif4gii antibody Anti-EIF4G3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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