產(chǎn)品詳情
簡單介紹:
Anti-EIF4A2 antibody (1-270) (STJ29906)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-EIF4A2 (1-270) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | EIF4A2 |
Gene ID: | 1974 |
Uniprot ID: | IF4A2_HUMAN |
Immunogen Region: | 1-270 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human EIF4A2 (NP_001958.2). |
Immunogen Sequence: | MSGGSADYNREHGGPEGMDP DGVIESNWNEIVDNFDDMNL KESLLRGIYAYGFEKPSAIQ QRAIIPCIKGYDVIAQAQSG TGKTATFAISILQQLEIEFK ETQALVLAPTRELAQQIQKV ILALGDYMGATCHACIGGTN VRNEMQKLQAEAPHIVVGTP GRVFDMLNRRYLSPKWIKMF VLDEADEMLSRGFKDQIYEI FQKLNTSIQVVLLSATMPTD VLEVTKKFMRDPIRILVKK |
Function | ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. |
Protein Name | Eukaryotic Initiation Factor 4a-Ii Eif-4a-Ii Eif4a-Ii Atp-Dependent Rna Helicase Eif4a-2 |
Database Links | Reactome: R-HSA-1169408 Reactome: R-HSA-156827 Reactome: R-HSA-429947 Reactome: R-HSA-72649 Reactome: R-HSA-72662 Reactome: R-HSA-72702 Reactome: R-HSA-72706 |
Alternative Antibody Names | Anti-Eukaryotic Initiation Factor 4a-Ii antibody Anti-Eif-4a-Ii antibody Anti-Eif4a-Ii antibody Anti-Atp-Dependent Rna Helicase Eif4a-2 antibody Anti-EIF4A2 antibody Anti-DDX2B antibody Anti-EIF4F antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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