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產(chǎn)品詳情
  • 產(chǎn)品名稱:Anti-EIF3J antibody (40-120 aa) (STJ92877)

  • 產(chǎn)品型號:STJ92877
  • 產(chǎn)品廠商:ST john's laboratory
  • 產(chǎn)品文檔:
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簡單介紹:
Anti-EIF3J antibody (40-120 aa) (STJ92877)
詳情介紹:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Eukaryotic translation initiation factor 3 subunit J (40-120 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EIF3J
Gene ID: 8669
Uniprot ID: EIF3J_HUMAN
Immunogen Region: 40-120 aa
Specificity: eIF3 Alpha Polyclonal Antibody detects endogenous levels of eIF3 Alpha protein.
Immunogen: Synthesized peptide derived from eIF3 Alpha at the amino acid range 40-120
Function Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
Protein Name Eukaryotic Translation Initiation Factor 3 Subunit J
Eif3j
Eukaryotic Translation Initiation Factor 3 Subunit 1
Eif-3-Alpha
Eif3 P35
Database Links Reactome: R-HSA-156827
Reactome: R-HSA-72649
Reactome: R-HSA-72689
Reactome: R-HSA-72695
Reactome: R-HSA-72702
Reactome: R-HSA-72706
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Eukaryotic Translation Initiation Factor 3 Subunit J antibody
Anti-Eif3j antibody
Anti-Eukaryotic Translation Initiation Factor 3 Subunit 1 antibody
Anti-Eif-3-Alpha antibody
Anti-Eif3 P35 antibody
Anti-EIF3J antibody
Anti-EIF3S1 antibody
Anti-PRO0391 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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