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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-EIF3I antibody (1-325) (STJ28665)

  • 產(chǎn)品型號(hào)：STJ28665
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-EIF3I antibody (1-325) (STJ28665)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EIF3I (1-325) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EIF3I
Gene ID: 8668
Uniprot ID: EIF3I_HUMAN
Immunogen Region: 1-325
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human EIF3I (NP_003748.1).
Immunogen Sequence: MKPILLQGHERSITQIKYNR EGDLLFTVAKDPIVNVWYSV NGERLGTYMGHTGAVWCVDA DWDTKHVLTGSADNSCRLWD CETGKQLALLKTNSAVRTCG FDFGGNIIMFSTDKQMGYQC FVSFFDLRDPSQIDNNEPYM KIPCNDSKITSAVWGPLGEC IIAGHESGELNQYSAKSGEV LVNVKEHSRQINDIQLSRDM TMFVTASKDNTAKLFDSTTL EHQKTFRTERPVNSAALSP
Post Translational Modifications Phosphorylated by TGF-beta type II receptor.
Function Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
Protein Name Eukaryotic Translation Initiation Factor 3 Subunit I
Eif3i
Eukaryotic Translation Initiation Factor 3 Subunit 2
Tgf-Beta Receptor-Interacting Protein 1
Trip-1
Eif-3-Beta
Eif3 P36
Database Links Reactome: R-HSA-156827
Reactome: R-HSA-72649
Reactome: R-HSA-72689
Reactome: R-HSA-72695
Reactome: R-HSA-72702
Reactome: R-HSA-72706
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Eukaryotic Translation Initiation Factor 3 Subunit I antibody
Anti-Eif3i antibody
Anti-Eukaryotic Translation Initiation Factor 3 Subunit 2 antibody
Anti-Tgf-Beta Receptor-Interacting Protein 1 antibody
Anti-Trip-1 antibody
Anti-Eif-3-Beta antibody
Anti-Eif3 P36 antibody
Anti-EIF3I antibody
Anti-EIF3S2 antibody
Anti-TRIP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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