產(chǎn)品詳情
簡單介紹：
Mouse NEP (Neprilysin) Sandwich ELISA Kit (STJE0010918)
詳情介紹：
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 33pg/mL |
| Detection Limit: | 78.1-5000pg/mL |
| Short Description: | This NEP Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | Mme |
| Gene ID: | 17380 |
| Uniprot ID: | NEP_MOUSE |
| Sample Type: | serum, plasma or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Myristoylation is a determinant of membrane targeting. Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity. |
| Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of the atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
| Protein Name | Neprilysin Atriopeptidase Enkephalinase Neutral Endopeptidase 24.11 Nep Neutral Endopeptidase Skin Fibroblast Elastase Sfe Cd Antigen Cd10 |
| Database Links | Reactome: R-MMU-2022377 Reactome: -MMU-5578768 Reactome: -MMU-6798695 |
| Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein |
| Alternative ELISA Names | Neprilysin ELISA kit Atriopeptidase ELISA kit Enkephalinase ELISA kit Neutral Endopeptidase 24.11 ELISA kit Nep ELISA kit Neutral Endopeptidase ELISA kit Skin Fibroblast Elastase ELISA kit Sfe ELISA kit Cd Antigen Cd10 ELISA kit Mme ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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