產(chǎn)品詳情
簡單介紹：
Anti-EIF2B5 antibody (442-721) (STJ112301)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF/IP |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-EIF2B5 (442-721) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 IP 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EIF2B5 |
| Gene ID: | 8893 |
| Uniprot ID: | EI2BE_HUMAN |
| Immunogen Region: | 442-721 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 442-721 of human eIF2B epsilon (eIF2B epsilon (EIF2B5) ) (NP_003898.2). |
| Immunogen Sequence: | TLPEGSVISLHPPDAEEDED DGEFSDDSGADQEKDKVKMK GYNPAEVGAAGKGYLWKAAG MNMEEEEELQQNLWGLKINM EEESESESEQSMDSEEPDSR GGSPQMDDIKVFQNEVLGTL QRGKEENISCDNLVLEINSL KYAYNISLKEVMQVLSHVVL EFPLQQMDSPLDSSRYCALL LPLLKAWSPVFRNYIKRAAD HLEALAAIEDFFLEHEALGI SMAKVLMAFYQLEILAEET |
| Post Translational Modifications | Phosphorylated at Ser-544 by DYRK2.this is required for subsequent phosphorylation by GSK3B. Phosphorylated on serine and threonine residues by GSK3B.phosphorylation inhibits its function. Polyubiquitinated, probably by NEDD4. |
| Function | Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. |
| Protein Name | Translation Initiation Factor Eif-2b Subunit Epsilon Eif-2b Gdp-Gtp Exchange Factor Subunit Epsilon |
| Database Links | Reactome: R-HSA-72731 |
| Alternative Antibody Names | Anti-Translation Initiation Factor Eif-2b Subunit Epsilon antibody Anti-Eif-2b Gdp-Gtp Exchange Factor Subunit Epsilon antibody Anti-EIF2B5 antibody Anti-EIF2BE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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