產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-EIF2B5 antibody (1-100) [S0MR] (STJ11102350)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-eIF2B epsilon (1-100) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: | Monoclonal |
Clone ID: | S0MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | EIF2B5 |
Gene ID: | 8893 |
Uniprot ID: | EI2BE_HUMAN |
Immunogen Region: | 1-100 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human eIF2B epsilon (EIF2B5) (EIF2B5) (Q13144). |
Immunogen Sequence: | MAAPVVAPPGVVVSRANKRS GAGPGGSGGGGARGAEEEPP PPLQAVLVADSFDRRFFPIS KDQPRVLLPLANVALIDYTL EFLTATGVQETFVFCCWKAA |
Post Translational Modifications | Phosphorylated at Ser-544 by DYRK2.this is required for subsequent phosphorylation by GSK3B. Phosphorylated on serine and threonine residues by GSK3B.phosphorylation inhibits its function. Polyubiquitinated, probably by NEDD4. |
Function | Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. |
Protein Name | Translation Initiation Factor Eif-2b Subunit Epsilon Eif-2b Gdp-Gtp Exchange Factor Subunit Epsilon |
Database Links | Reactome: R-HSA-72731 |
Alternative Antibody Names | Anti-Translation Initiation Factor Eif-2b Subunit Epsilon antibody Anti-Eif-2b Gdp-Gtp Exchange Factor Subunit Epsilon antibody Anti-EIF2B5 antibody Anti-EIF2BE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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