產(chǎn)品詳情
簡單介紹:
Mouse MTMR9 (Myotubularin Related Protein 9) Sandwich ELISA Kit Ready-To-Use (STJE0017152)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.058ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This MTMR9 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Mtmr9 |
Gene ID: | 210376 |
Uniprot ID: | MTMR9_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | |
Function | Acts as an adapter for myotubularin-related phosphatases. Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate, and MTMR6 binding affinity for phosphorylated phosphatidylinositols. Positively regulates lipid phosphatase MTMR7 catalytic activity. The formation of the MTMR6-MTMR9 complex, stabilizes both MTMR6 and MTMR9 protein levels. Plays a role in the late stages of macropinocytosis possibly by regulating MTMR6-mediated dephosphorylation of phosphatidylinositol 3-phosphate in membrane ruffles. Negatively regulates DNA damage-induced apoptosis, in part via its association with MTMR6. Does not bind mono-, di- and tri-phosphorylated phosphatidylinositols, phosphatidic acid and phosphatidylserine. |
Protein Name | Myotubularin-Related Protein 9 Inactive Phosphatidylinositol 3-Phosphatase 9 |
Database Links | Reactome: R-MMU-1660499 |
Cellular Localisation | Cytoplasm Cell Projection Ruffle Membrane Peripheral Membrane Protein Cytoplasmic Side Perinuclear Region Endoplasmic Reticulum Localizes To Ruffles During Egf-Induced Macropinocytosis Colocalizes With Mtmr6 To The Perinuclear Region Partially Localizes To The Endoplasmic Reticulum |
Alternative ELISA Names | Myotubularin-Related Protein 9 ELISA kit Inactive Phosphatidylinositol 3-Phosphatase 9 ELISA kit Mtmr9 ELISA kit Mtmr3 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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